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biomiblab@bme.gatech.edu
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Since August 3rd, 2009

Mission
Research Scope
National Vision
Sponsors & Partnerships
Bio-MIBLab Mission
Advanced bio-technologies such as gene expression microarrays, next-generation sequencing, proteomics, molecular imaging, metabolomics, and lipidomics have expedited research in molecular biology and molecular medicine. These technologies have identified biomarkers in humans that may provide improved diagnostic or prognostic information. The big challenge now is the huge volume of data that is waiting to be analyzed and interpreted. With this critical need, the mission of the Bio-MIBLab (Bio-Medical Informatics and Bioimaging Laboratory) is to accelerate the early detection, diagnosis, prognosis, treatment, and prevention of disease through translational medicine using advanced bio-computing techniques for bioinformatics, systems biology, and molecular image processing research.
Research Scope
Research in the Bio-MIBLab is divided into four project tracks:
  1. High-Throughput -Omic and Next-Generation Sequencing
  2. Molecular and Cellular Imaging Informatics for Next-Generation Pathology
  3. Modeling for Systems Biology and Systems Medicine
  4. Mobile Health and Health Informatics
The first project track focuses on data analysis pipelines for quality control of .omic data, identification of genomic and proteomic biomarkers, and development of clinical prediction models. The second project track focuses on analysis of biomedical imaging data (e.g., histopathological images) to extract informative features, identify morphological biomarkers, and develop clinical prediction models. The third project track focuses on analysis of biomolecular interaction to understand the underlying mechanisms of metabolism, pharmacokinetics, and gene regulation in molecular biology and medicine. The fourth project track focuses on development of mobile health technologies to aide in acquiring, delivering, and analyzing health informatics data.

The Bio-MIBLab has had a major impact in the research and clinical communities through the numerous lab publications and software applications.
National Vision
In November of 2003, the NIH announced a roadmap called "New Pathways to Discovery". This roadmap includes five priorities: (1) building blocks, biological pathways, and networks; (2) molecular libraries and molecular imaging; (3) structural biology; (4) bioinformatics and computational biology; and (5) nanomedicine.

Bio-MIBLab's translational computation research matches four of the top five priorities. The lab has been playing an important role in several federal- and state-supported large research efforts.
Sponsors & Partnerships
The Bio-MIBLab partners with two computing industry giants, Hewlett Packard and Microsoft Research, to establish not only a strong computing infrastructure, but also to fulfill long term goals through research collaborations.

The Bio-MIBLab is also part of the Winship Cancer Institute at Emory University Medical School. Together, with multiple committed translational researchers in cancer, neuromedicine, and molecular and genetic biology, the Bio-MIBLab has been able to tackle translational problems such as renal cancer, prostate cancer, breast cancer, ovarian cancer, schizophrenia, and fundamental problems in molecular and genetic biology.

Other research sponsors include: NIH, Georgia Cancer Coalition, Georgia Research Alliance, IBB, and Johnson & Johnson.

Click here for a full list of sponsors and partnerships.